Medical Director, Cardiovascular

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Medical Director, Cardiovascular

MannKind Corporation (Nasdaq: MNKD) is a biopharmaceutical company dedicated to transforming chronic disease care through innovative, patient-centric solutions. Focused on cardiometabolic and orphan lung diseases, we develop and commercialize treatments that address serious unmet medical needs, including diabetes, pulmonary hypertension, and fluid overload in heart failure and chronic kidney disease. With deep expertise in drug-device combinations, MannKind aims to deliver therapies designed to fit seamlessly into daily life. At MannKind, our employees are our greatest asset. We foster a close-knit, collaborative culture where every team member plays a vital role in our mission. We are proud to champion a rich blend of backgrounds, perspectives, and working styles as we work together to improve health outcomes and change lives.

Position Summary

The Medical Director, Cardiovascular is a respected medical leader and subject matter expert in heart failure and fluid overload who influences the advancement of innovative therapies through strategic clinical guidance and scientific leadership. Partnering closely with Clinical Development, Medical Affairs, and Commercial teams, this role provides expert input on development-stage and postmarketing programs, helping shape evidence generation and medical strategy. The Medical Director serves as a trusted scientific voice for the organization, ensuring clinical integrity, meaningful stakeholder engagement, and alignment with the company's vision for improving patient outcomes. The Medical Director provides strategic leadership for Translational Medicine, Clinical Development, Clinical Operations, Biostatistics/Data Management, Medical Affairs, Drug Safety / Pharmacovigilance, and Regulatory Affairs to advance integrated development and lifecycle planning. The Medical Director also provides cross-functional scientific leadership and medical expertise to commercial and market access counterparts.

Key Responsibilities

  • Therapeutic Area Leadership & Strategy
  • Clinical Study Planning & Design
  • Clinical Study Execution & Oversight
  • Regulatory Leadership & Scientific Communication
  • Medical Affairs Collaboration
  • Data Analysis, Interpretation & Strategic Insight Integration
  • Cross-Functional Leadership & Enterprise Influence
  • People Leadership & Organizational Development

Education and Experience Qualifications

  • M.D. required, with clinical experience in medical practice preferred, ideally as a cardiologist, critical care physician, or nephrologist. An additional PhD, MPH, or MBA also highly valued.
  • 5+ years of progressive medical affairs and/or clinical development experience within the pharmaceutical or biotechnology industry.
  • Demonstrated expertise in cardiovascular disease (and specific experience in congestive heart failure strongly preferred).
  • Track record of designing and executing clinical trials in cardiovascular chronic disease populations (and experience with wearable devices preferred)
  • Proven ability to lead and influence cross-functional teams, collaborate effectively with investigators and scientific leaders, and represent programs in global regulatory interactions.
  • Exceptional scientific communication, analytical, and leadership capabilities, with the ability to convey complex clinical concepts to diverse internal and external stakeholders.
  • Ability and willingness to travel approximately 20%, primarily domestically, with occasional international travel.

Industry Knowledge

  • Deep understanding of clinical development methodologies, including biomarker strategy, pK/pD principles, translational medicine approaches, and regulatory pathways for cardiorenal diseases.
  • Knowledge of U.S. (and ex-U.S.) regulatory and clinical research requirements relevant to cardiovascular drug development.
  • Demonstrated ability to integrate scientific insights, regulatory expectations, competitive intelligence, and operational considerations into cohesive, forward-looking development strategies.
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