Senior Director, Clinical Business Planning

Senior Director, Clinical Business Operations And Strategy

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigorall in service of patients.

The Opportunity

Revolution Medicines is focused on developing targeted therapies for patients with RAS-addicted cancers. The Senior Director, Clinical Business Operations and Strategy will lead the financial and business planning capabilities that support delivery of the global clinical development portfolio.

As a member of Clinical Operations, this leader will oversee study and departmental budgets, forecasting, workforce and resource planning, vendor financial management, and investigator site budgets and payments. Working closely with Clinical Operations leadership and Finance, the Senior Director will translate clinical development priorities into funded, achievable operating plans and provide clear recommendations on spending, capacity, and financial risk.

The role will lead and develop the Clinical Business Operations and Strategy team and partner with study teams, Global Vendor Outsourcing, Finance, Legal, and other development functions to maintain reliable financial information and support timely study delivery. The lead will oversee a team that does the following:

Key Responsibilities:

• Clinical budgeting and forecasting
• Clinical Operations resource planning
• Vendor budgets and invoice oversight
• Site budgets and payment forecasting
• Business strategy and operational improvement
• Team leadership and collaboration

Location and Travel

The ideal candidate is based in the Bay Area and available to work onsite in Redwood City as needed, up to approximately three days per week. Travel may be required, approximately 25%.

Required Skills, Experience and Education:

• BA or BS, plus 17+ years of experience or equivalent and 10+ years at a leadership role. Advanced degree desirable: Masters(MBA), 15+ years experience and 8+ years leadership or Doctoral, 13+ years experience and 6+ years leadership.
• Progressive responsibility in clinical business operations, clinical financial management, or Clinical Operations within biotechnology or pharmaceutical organizations, including leadership of complex global clinical budgets.
• Expertise in the operational and financial drivers of large, multisite oncology trials across early and late development and postmarketing studies.
• Demonstrated ability to build and manage study and portfolio budgets, forecasts, accrual inputs, variance analyses, and financial scenarios in close partnership with Finance.
• Experience planning Clinical Operations headcount and capacity, allocating internal and external resources, and assessing the cost implications of changing portfolio demand.
• Strong understanding of CRO and vendor budgets, statements of work, change orders, invoice review, and financial reconciliation, together with global investigator site budgets and payment forecasting.
• Proven ability to lead teams, manage organizational change, establish scalable processes, and communicate financial recommendations to senior leaders and cross-functional partners.
• Advanced Excel and financial modeling skills, strong analytical judgment, and the ability to reconcile complex data while managing competing priorities.

• Excellent organizational and time management skills along with strong attention to detail. Proven ability to handle multiple tasks efficiently and effectively.
• Comfortable in a fast-paced company environment and able to adjust workload based upon changing priorities.
• Experience leading strategic change management initiatives across clinical operations or equivalent.
• Excellent interpersonal, verbal, and written communication skills, with ability to interact with colleagues and partners at all levels of experience.
• Ability to produce, interpret and share complex performance information and communicate it to a wide variety of audiences.
• Experience with hiring, training, developing, mentoring, and motivating team members to the highest level of performance.
• An innovative, driven, and effective person with a "can do" attitude.
• A goal-oriented person who can plan for the long-term and execute stated objectives.
• Travel may be required (~25%).

Preferred Skills:

• Advanced degree in business, finance, life sciences, or a related field; experience in a growing biotechnology company or department.
• Experience with financial planning and enterprise resource planning systems, clinical trial management systems, site payment platforms, and reporting or visualization tools.
• Experience implementing budget and resource planning tools; proficiency with Smartsheet, PowerPoint, and other business reporting applications.
• Knowledge of international clinical trial operations and working familiarity with applicable ICH and Good Clinical Practice guidelines.
• Knowledge and/or familiarity with Ex-US region(s) clinical trial operations.
• Global Project Level Budget Builds.
• Advanced knowledge of Microsoft Word, Excel, PowerPoint and Smartsheet.

Base Pay Salary Range $244,000 $305,000 USD