Postdoctoral Research Scientist

Position Description

The Department of Dermatology at Vagelos College of Physicians and Surgeons of Columbia University invites applications for a postdoctoral research scientist position in the laboratory of Dr. Annemieke de Jong. The Department of Dermatology is an exciting multidisciplinary workplace with excellent resources. The de Jong lab is seeking a creative and highly motivated individual with an interest in human T cell biology and skin immunology. The successful applicant will be working in a dynamic research environment with opportunity to gain research experience and receive excellent mentoring.

The position is for an immunology project that aims to better understand the functions and antigen specificities of human unconventional T cell subsets. The lab is particularly focused on CD1-restricted T cells that respond to lipid antigens rather than peptide antigens. These T cells can be activated by changes in the lipid environment that occur in inflammation, infection, and cancer, but their exact functions and regulation in homeostasis and disease remain incompletely understood. The ideal candidate will have a strong background in immunology and T cell biology.

Roles and Responsibilites

* Design and perform immunological assays, collect and analyze data

* Isolate and phenotype human T cell populations and maintain in culture

* Visualize and interpret datasets, and use to formulate new hypotheses

* Work collaboratively with other members of the lab and the department

* Present data in weekly lab meetings and at conferences

* Contribute to manuscript preparation and fellowship applications

Qualifications

* Ph.D., M.D./Ph.D., M.D. in Immunology or a related field

* Strong laboratory, analytical, interpersonal and communication skills.

Preferred Qualifications

* Competence with flow cytometry (including spectral)

* Sterile cell culture methods and cell isolation techniques

* Immunoassays (Elispot / ELISA) and T cell activation assays

* Single cell RNA-seq/TCR-seq using platforms such as 10x Genomics

* Familiarity with computational analysis of single cell GEX/TCR data

* Background in T cell biology is an asset

Application instructions

APPLICATION

Applicants are requested to submit the following materials as a single PDF:

* Cover letter describing research interests, experience, relevant skills, and career goals

* Curriculum Vitae

* Contact information for 3 references familiar with the applicant's research and qualifications

Please send complete applications to [email protected]

Equal employment opportunity statement

Columbia University is an Equal Opportunity Employer / Disability / Veteran

Pay Transparency Disclosure

The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.